Several players will begin a warm weather training camp in Dubai this week in a bid to boost their fitness.
United players flew out on Monday to take part in the camp, which will be held over the international break.
There are fitness worries about both Marcos Rojo and Scott McTominay. Rojo pulled out of the Argentina squad on Sunday after coming on as a second-half substitute during the win over Brighton while McTominay is set to have a scan on his ankle after being stretchered off in the last minute of Sunday’s game.
The midfielder is due to be on international duty with Scotland but could be forced to withdraw from their Euro 2020 qualifiers depending on the severity of his injury.
David de Gea, Harry Maguire, Daniel James, Victor Lindelof and Marcus Rashford will not be part of the squad that has travelled to Dubai for warm weather training due to international commitments.